A physiological response to myocardial ischemia is the remodeling of collateral blood vessels to accept increased flow and thereby bypass stenotic regions. Two-thirds of patients with critical narrowing of a coronary artery (>70% reduction in diameter) have one or more collateral vessels.. Semenza, G. L. Hypoxia-inducible factors in physiology and medicine. Cell 148 , 399-408 (2012). CAS PubMed PubMed Central Google Scholar

Hypoxiainducible factor regulation is shown. Under normal condition,... Download Scientific
Hypoxia inducible factor (HIF) and vascular endothelial growth factor... Download Scientific

Redox Regulation of HypoxiaInducible Factors Encyclopedia MDPI

Hypoxiainducible factor pathway in angiogenesis at hypoxia and... Download Scientific Diagram

Hypoxia inducible factor1 alpha (HIF1α) is a central transcription... Download Scientific

Regulation of hypoxia inducible factor1 (HIF1) activity. An... Download Scientific Diagram

HypoxiaInducible Factors in Physiology and Medicine Cell

Physiological effects of hypoxiainducible factor 1 (HIF1) hypoxia... Download Scientific

Chronic hypoxia and the cerebral circulation Journal of Applied Physiology

Hypoxiainducible factor1 a (HIF1 a ) and vascular endothelial growth... Download Scientific

Hypoxiainducible factors in the kidney American Journal of PhysiologyRenal Physiology

Explanation video the role of the hypoxia inducible factor (HIF) in the regulation of oxygen

Frontiers HypoxiaInducible Factor Regulates Endothelial Metabolism in Cardiovascular Disease

Inhibitors of the hypoxiainducible factor (HIF) pathway currently... Download Scientific Diagram

HIF1α (HypoxiaInducible Factor1α) Promotes Macrophage Necroptosis by Regulating miR210 and

Regulation of hypoxia inducible factor1 α (HIF1α) stability and HIF1... Download Scientific

Hypoxiainducible factorprolyl hydroxylase inhibitors in the treatment of anemia of chronic

Potential central role of low hypoxia inducible factor1α (HIF1α)... Download Scientific Diagram

HypoxiaInducible Factors in Physiology and Medicine Cell

Regulation of hypoxiainducible factors. In normoxia, HIF1 a is... Download Scientific Diagram
Cells of the immune defence, especially leukocytes, often have to perform their function in tissue areas that are characterized by oxygen deficiency, so-called hypoxia. Physiological hypoxia significantly affects leukocyte function and controls the innate and adaptive immune response mainly through transcriptional gene regulation via the hypoxia-inducible factors (HIFs). Multiple pathogens.. A crucial oxygen-sensing effector is the transcription factor Hypoxia-Inducible Factor 1 (HIF1), a heterodimeric protein containing an oxygensensitive α subunit and a nuclear localized stable β.